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Project 2 (University of Göttingen)

Characterization of cerebral alterations in children with unclassified and rare classified leukodystrophies using multiparametric magnetic resonance investigations


Among the leukoencephalopathies a large proportion remains still unclassified. This project aims to investigate these patients with multiparametric magnetic resonance examinations which involve localized proton MR spectroscopy, diffusion tensor imaging and quantitative MRI mapping of magnetization transfer. This may reveal metabolic and diffusional abnormalities to further classify this group of diseases and to elucidate pathophysiologic mechanisms underlying these disorders.


Investigators:


Knut Brockmann, Steffi Dreha-Kulaczewski


Contact:


Prof Dr. med. Knut Brockmann
Abteilung Pädiatrie II
Robert-Koch-Strasse 40
D-37075 Göttingen
Phone +49 (0) 551 396299
Fax +49 (0) 551 396252
Email:
kbrock@med.uni-goettingen.de 



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